Although top spot in Group in D was not out of reach for either side before kick-off, Serbia's 1-0 victory over Georgia gained them automatic qualification to Russian Federation 2018 and forced Martin O'Neill's side into the play-offs.
A draw would be enough for Wales to stay in second place, but this wouldn't guarantee a play-off spot for Russian Federation 2018.
But what results do we need to make it to Russian Federation?
Best remembered for the one-off usage of an all-grey kit, it was the last competitive game played before the glory days of the Giovanni Trapattoni era.
The 1958 tournament in Sweden was the only previous time that Wales have reached the World Cup finals, making it all the way to the quarter-finals before losing 1-0 to Brazil.
'But if we keep doing what we've been doing, it will give us a chance of having a good night [tonight].' Coleman has dismissed talk of a grudge match after what happened when the sides met in March. They would top the group if Serbia lost to Georgia.
The game against Moldova was always going to be about the result only, with anything other than three points sure to end Ireland's hopes.
The draw does not favor the Irish side at all and it will go all out to try and get the win at Cardiff City Stadium.
It follows on from 2,000 travelling fans belting out the tune prior to the 1-0 over win over Georgia on Friday despite attempts from the hosts to quash the away support and their singing.
School guard sets kids on fire
Some of the patients are being airlifted to a specialised burns unit in the state capital, Belo Horizonte. The guard, who had helped with security at the center since 2008, died hours later in a local hospital.
Amir ruled out of Sri Lanka ODI series
The match will be the sixth day-night Test after the first between Australia and New Zealand at Adelaide in 2015. The left-arm pacer bowled two overs on Day 2 but left the field again, then was being taken to a hospital.
Ukip elects Henry Bolton as the party's new leader
Farage told Channel 4's Michael Crick that he voted for Bolton, describing him as the "most competent" candidate in the running. Mr Etheridge was one of a number of UKIP MEPs who had threatened to quit the party if bookies favourite Ms Waters had won.
Highlights of Wednesday's Major League Baseball games
Still, there was an argument to be made that the series loss was an isolated incident, and the Cardinals future remained bright. The third baseman doubled home a run in the 11th inning Thursday night, giving the Cubs a 2-1 victory.
Iran slaps fuel trade embargo on Iraqi Kurdistan
It went on to say the people of Iraq should avoid "anything that might harm the national unity of Iraq's communities". Prime Minister Haider al-Abadi wants the referendum , in which 92% of voters backed secession, to be annulled.
Clean Energy Revolution Shatters Records & Projections
And for the first time in USA history, wind and solar energy made up more than 10 percent of all monthly electricity generation. This higher forecast is because of increase in predictions of China and India's solar PV additions.